Bio-Rad’s range of ready-made anti-biotherapeutic antibodies enables the development of robust and reliable bioanalytical assays against marketed biologic drugs. The new anti-idiotypic antibodies are suitable for pharmacokinetic (PK) and antidrug-antibody assays for atezolizumab, avelumab, obinutuzumab, and ocrelizumab, enabling therapeutic drug monitoring for innovator and biosimilar products.
The anti-MMAE antibody range supports bioanalysis of antibody-drug conjugates (ADCs) carrying MMAE as payload. MMAE is a potent antimitotic agent that inhibits cell division. Due to its toxicity, MMAE is not used as a drug itself, but instead forms the payload component of ADCs. Bio-Rad’s new anti-MMAE biotherapeutic antibodies enable the development of sensitive assays for both ADCs incorporating the toxin, or the toxin itself.
“Bio-Rad’s extensive range of anti-biotherapeutic antibodies offers an effective solution to drug-specific bioanalytical assay development, enabling design of selective, sensitive, and reliable PK and ADA assays,” said John Cardone, Marketing Manager, Life Science Group, Bio-Rad. “Introduction of the new drug-specific and MMAE anti-biotherapeutic antibodies further expands the utility of our market-leading portfolio of over 200 anti-idiotypic antibodies, providing our customers with new and innovative bioanalysis tools to accelerate antibody drug discovery.”
To learn more about Bio-Rad’s anti-idiotypic antibodies, visit bio-rad.com/biotherapeutic-antibodies
BIO-RAD is a trademark of Bio-Rad Laboratories, Inc. in certain jurisdictions. Products containing SpyTag1, SpyTag3, SpyCatcher1 or SpyCatcher3 and/or their use are covered by the following U.S. patents and/or pending U.S. patent application or their foreign counterparts owned by or under license to Bio-Rad Laboratories, Inc., including, but not limited to, U.S. Patent Nos. 9,547,003, 10,247,727, and 10,527,609. Products containing SpyTag2 or SpyCatcher2 and/or their use are covered by the following U.S. patents and/or pending U.S. patent application or their foreign counterparts owned by or under license to Bio-Rad Laboratories, Inc., including, but not limited to, U.S. Patent Nos. 9,547,003, 10,247,727, 10,527,609, and 11,059,867
