Paragonix Technologies, an organ transplant solutions provider, has completed its first paediatric liver transplant using the LIVERguard Donor Liver Preservation System.

The LIVERguard system was used to preserve the donor’s liver. The procedure was performed at Duke University Hospital in Durham, North Carolina.

Paragonix Technologies introduced the LIVERguard Donor Liver Preservation System in 2022.

Since its launch, the system has been utilised in over 300 liver transplant cases in the US.

Recent clinical presentations have highlighted the LIVERguard System’s efficacy in reducing post-transplant complications compared to traditional ice storage.

These findings come from the GUARDIAN-LIVER global clinical registry, a study designed to evaluate the effects of various liver preservation and transportation methods.

The LIVERguard system has been adopted by liver transplant centres across the US, supporting the procurement and allocation of donor livers.

It includes facilitating long-distance procurements from places like Puerto Rico and Hawaii and enabling Organ Procurement Organisations (OPOs) to place high-risk donor livers.

Paragonix Technologies CEO and president Lisa Anderson said: “We are thrilled to see our technology utilised in the paediatric setting, extending its impact to more liver transplant patients and improving preservation techniques and outcomes for children.

“Partnering with a leading paediatric liver transplant centre like Duke University, whose mission it is to provide extraordinary care aligns perfectly with our vision of improving outcomes. It is truly exciting to work together to transform the healthcare system for the better.”

The LIVERguard System is designed to offer a controlled environment for hypothermic liver preservation.

It features real-time digital monitoring technology to safeguard the liver of organ donors throughout the entire transplant process.  

In contrast to traditional methods that rely on ice and standard coolers, the LIVERguard advances the organ transplantation technology, Paragonix claimed.

In February last year, the organ transplant solutions developer announced the first paediatric use of the LUNGguard System in a time-shift lung transplantation case.

In June this year, Paragonix Technologies unveiled the PancreasPak Organ Preservation System to safeguard and monitor donor pancreases during transportation.